Screenshot_2025-09-12_at_11.46.51_AM.png
Where science meets timeless beauty

PROVOQUE™ The Future of Regenerative Skincare

Powered by the complete skin secretome, growth factors, exosomes, and fetuin-A, PROVOQUE helps skin renew itself. Expect smoother texture, firmer tone, radiance, and fewer fine lines in as little as 14 days. Real science. Real transformation.

Screenshot_2026-01-06_at_1.10.26_PM.png
Screenshot_2026-01-06_at_1.10.34_PM.png

Developed by Experts.
Proven by Science.

Created by Dr. Laura Ellis and Dr. Hans Keirstead, PROVOQUE is built on peer-reviewed regenerative research and validated trials. Independent studies show improvements in as little as 14 days, with measurable collagen gains by 12 weeks, setting a new standard in skincare innovation.

This platform that powers PROVOQUE™, LevEllis’ flagship skincare innovation, is built upon this skin-specific cellular science. These young, skin-derived progenitor cells produce a complete skin secretome — a robust, biologically active blend of naturally occurring growth factors, exosomes, and the critical glycoprotein fetuin-A. 

Fetuin-A plays a pivotal role in skin health and acts as a biologic “keychain,” enabling the controlled delivery and absorption of regenerative factors deep into the skin. 

SIGNS OF IMPROVEMENTS IN 12-WEEKS

Overall skin rejuvenation for provocative results

Percentage Improvement in Key Skin Metrics: Dermatologist’s Assessment

Unlocking the Skin Secretome
Most products rely only on growth factors or exosomes. PROVOQUE combines bothplusfetuin-A for deeper regeneration, mimicking the skin’s natural healing.
Visible Results, Backed by Data
  • Smoother, healthier skin in 14 days
  • Reduced fine lines, improved texture and radiance within 4 weeks
  • Ongoing gains through 12 weeks
  • Clinically proven 25% collagen increase (biopsy verified)
Screenshot_2025-09-12_at_11.47.11_AM.png
Unlocking the Skin Secretome
Most products rely only on growth factors or exosomes. PROVOQUE combines bothplusfetuin-A for deeper regeneration, mimicking the skin’s natural healing.
Screenshot_2025-09-12_at_11.47.52_AM.png
Visible Results, Backed by Data
  • Smoother, healthier skin in 14 days
  • Reduced fine lines, improved texture and radiance within 4 weeks
  • Ongoing gains through 12 weeks
  • Clinically proven 25% collagen increase (biopsy verified)

Inside PROVOQUE™

Growth Factors

The body’s natural messengers that tell skin cells to repair, renew, and produce collagen. They help restore firmness, elasticity, and youthful resilience.

Exosomes

Microscopic vesicles that carry signals between cells. They enhance skin’s ability to respond to stress, boost hydration, and improve texture by supporting healthy cellular communication.

Fetuin-A (exclusive to PROVOQUE™)

A breakthrough addition found only in this formula. Fetuin-A regulates how growth factors and exosomes are received, unlocking their full regenerative potential. It’s the “conductor” that ensures every element works in harmony for faster, more visible results

This precise blend is what transforms PROVOQUE™ from a serum into a luxury ritual, delivering the timeless beauty of regeneration.